I’m getting a noticeable delay. It used to only happen when I opened something old I rarely accessed, but now it happens in most Gnome apps. They are fast once they load. I don’t know if there is something happening with encryption or compression, or if it is my drive’s wear. I’m not really sure how to diagnose this one in a meaningful way. On Workstation 42 mostly defaults and from an upgrade path since 36 on this machine IIRC.
It could be an issue with dbus not starting properly. Check to see if dbus access is timing out.