I would recommend Unraid. Not sure what people think of it round here as surprised no one has mentioned it. My homelab was a mix of machines for VMs, Docker and NAS, and I consolidated it last year with Unraid and couldn’t be happier. I run Plex, Immich, Wordpress, Home Assistant and a load of other containers, alongside a Windows and Ubuntu VM on a cheap eBay HP Z workstation. If on a NUC with only a single drive, V7 of Unraid will now work without an array, so a single drive basically. It’ll give you a GUI for Docker and everything.
I would recommend Unraid. Not sure what people think of it round here as surprised no one has mentioned it. My homelab was a mix of machines for VMs, Docker and NAS, and I consolidated it last year with Unraid and couldn’t be happier. I run Plex, Immich, Wordpress, Home Assistant and a load of other containers, alongside a Windows and Ubuntu VM on a cheap eBay HP Z workstation. If on a NUC with only a single drive, V7 of Unraid will now work without an array, so a single drive basically. It’ll give you a GUI for Docker and everything.